Phase 1: Cardiovascular Prototype (MVP)

Timeline:
6–8 weeks

Investment:

$17,000 labor (rate discounted 15%)

$1,000 technical resources (estimated)

Objectives

Deliver a cardiology-focused MVP for user testing, prioritizing rapid development, synthetic data safety, and foundational compliance.

Key Deliverables

NLP Pipeline for Cardiology Notes: Extracts EF, valve pathology, and symptoms from synthetic notes.

Synthetic Data Integration: Uses Gretel.ai to generate anonymized clinical notes for development.

Clinician Demo Interface: React.js frontend for small-group user testing.

Sprints

Sprint

1

2

3

Focus

Data pipeline setup

LLM fine-tuning

User testing prep

Roles

AI Specialist (80hrs), Backend (40hrs)

AI Specialist (60hrs), UI/UX (30hrs)

PM (20hrs), Backend (20hrs)

Gretel.ai Key Advantages Over Traditional Anonymization

No Data Loss: Synthetic data retains rare edge cases (e.g., outlier lab values) often redacted in anonymization

Faster Access: Bypass months-long IRB approvals; generate compliant datasets in hours

Ethical AI: Reduces bias in models by augmenting underrepresented groups (e.g., minority demographics)

For healthcare organizations, Gretel.ai bridges the gap between innovation and compliance, enabling safer, faster AI development without compromising patient trust. Explore Gretel’s documentation or GitHub repos for implementation guides.

Why Gretel.ai Was Chosen for Simulated Healthcare Datasets

Gretel.ai is a leading synthetic data platform selected for its ability to balance privacy, utility, and regulatory compliance in healthcare applications. Here’s why it stands out:

HIPAA Compliance and Privacy Safeguards

Gretel generates synthetic data that mimics real patient records without exposing sensitive PHI (Protected Health Information). Its anonymization techniques, such as differential privacy and data masking, ensure compliance with regulations like HIPAA and GDPR.

Unlike traditional anonymization, which risks re-identification, Gretel’s synthetic data cannot be reverse engineered to trace back to individuals.

High Fidelity to Real-World Data

Gretel’s models (e.g., ACTGAN, Amplify) replicate statistical patterns, correlations, and distributions of real datasets. For example, synthetic patient age distributions in clinical trials closely mirror original data, preserving critical trends like disease prevalence across demographics.

In benchmark tests, Gretel’s synthetic data achieved <2% accuracy loss compared to real data in downstream tasks like heart disease prediction.

Scalability for Complex Use Cases

Gretel supports relational databases, enabling synthetic versions of multi-table EHR systems (e.g., patient records linked to lab results and treatments). This ensures referential integrity and realistic data relationships.
It scales to generate large datasets (e.g., 10k+ synthetic patient records) efficiently, addressing data scarcity in rare diseases or underrepresented populations.

Bias Mitigation
By augmenting imbalanced datasets (e.g., boosting female patient records in male-dominated heart disease data), Gretel reduces algorithmic bias. One case saw a 13% accuracy gain in models trained on synthetic-augmented data.

Use Cases

Train AI models for early disease detection

Simulate rare medical events (e.g., sudden EF decline) for research

How Gretel.ai Works: Step-by-Step Process

Data Ingestion and Preprocessing

Upload real datasets (CSV, SQL, FHIR) or connect to databases (e.g., Epic, Cerner).

Gretel automatically detects relationships (e.g., primary/foreign keys in relational databases)

Model Selection and Training

ACTGAN: For tabular data (e.g., patient demographics)

Amplify: For relational databases (e.g., EHR systems with linked tables)

Navigator: For complex workflows (e.g., safety-aligned LLM responses)

Models train on real data to learn distributions, correlations, and constraints (e.g., lab value ranges)

Synthetic Data Generation

Generate data with customizable volume (e.g., 5k synthetic patient records)

Preserve relational integrity: A synthetic patients table links to lab_results and treatments with realistic one-to-many relationships

Validation and Quality Assurance

Statistical Reports: Compare synthetic vs. real data distributions (e.g., age, diagnosis codes)

Privacy Checks: Metrics like Synthetic Quality Score (SQS) evaluate re-identification risk and utility

Clinical Validation: Clinicians review synthetic summaries for workflow alignment

Deployment

Export synthetic data to FHIR APIs, cloud storage (GCP/AWS), or EMR sandboxes

Investment Breakdown

Human Resources: $17,000

AI Specialist:

Design NLP pipeline for cardiovascular concepts

Fine-tune LLMs on synthetic cardiology notes

Backend Developer:

Set up GCP data pipelines

Integrate synthetic data tools

UI/UX Designer:

Build clinician demo interface

Project Management:

Coordinate sprints and client updates

Technical Resources: $1,000

Gretel.ai: Synthetic data generation ($500)

GCP Prototyping Tier: Non-HIPAA cloud compute ($300)

Firebase: Real-time testing database ($200)